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| Important Troxygen Information |
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Ozone was first discovered and named by German scientist C.F. Schonbein in 1840
- The first ozone generators were developed by Werner von Siemens in Germany in 1857. The first report of ozone being used to purify blood in test tubes was by the German Dr. C. Lender in 1870.
- The first American therapeutic use of ozone was by Dr. John H. Kellogg in ozone steam saunas at his Battle Creek, Michigan sanitarium from 1880, as he wrote in his book, " Diphtheria: Its Nature, Causes, Prevention and Treatment".

- In October 1893, the world's first water treatment plant using ozone was installed in Ousbaden, Holland, and today there are over 3000 municipalities around the world that use ozone to clean their water and sewage, including all the great cities.

- 1886: The ability of ozone to disinfect polluted water is recognized in Europe.
- 1891: Test results from Germany show that ozone is effective against bacteria.
- 1893: First full-scale application using ozone for drinking water in the Netherlands.
- In 1902, J.H. Clarke's "A Dictionary of Practical Materia Medica", London, describes the successful use of ozonated water ("Oxygenium") in treating anemia, cancer, diabetes, influenza, morphine poisoning, canker sores, strychnine poisoning and whooping cough.
- 1906: Nice, France commissions first municipal ozone plant for drinking water.
- 1911: "A Working Manual of High Frequency Currents" was published by Dr. Noble Eberhart, MD, the head of the Dept. of Physiologic Therapeutics at Loyola University, Chicago. In Chapter 9, he details the use of ozone to treat tuberculosis, anemia, chlorosis, tinnitus, whooping cough, asthma, bronchitis, hay fever, insomnia, pneumonia, diabetes, gout and syphilis.
- 1914: World War I – Poisonous gas research leads to the development of inexpensive chlorine gas. Interest in ozone for water begins to decline.
- 1915: At least 49 major ozone installations are on line throughout Europe.
- 1926: Dr. Otto Warburg of the Kaiser Institute in Berlin announced that he had found that the cause of cancer is a lack of oxygen at the cellular level. For his discovery, he was awarded the Nobel Prize for Medicine in 1931 and again in 1944, the only person ever to receive two Nobel Prizes for medicine. He was also nominated for a third.
- 1929: a book called "Ozone and Its Therapeutic Action" was published in the US listing 114 diseases and how to treat them with ozone. Its 40 authors were the heads of all the leading American hospitals.
- 1957: Ozone is implemented for oxidation of iron and manganese in Germany.
   
- 1964: Spontaneous flocculation in ozone contact chambers led to France constructing an ozone plant to enhance particulate removal.
- 1965: Scotland employs ozone for color control in surface water. Switzerland uses ozone to oxidize micro pollutants such as phenolic compounds and several pesticides.
- 1970's: French exploit use of ozone for algae control.
- 1980:Dr. Horst Kief also reported success with ozone therapy for AIDS patients.
- 1982: FDA GRAS (generally regarded as safe) declaration for ozone use in bottled water.
- 1987: City of Los Angeles 600 MGD ozonation plant comes on line after 7 years of pilot testing.

- 1988: Dr. Gerard Sunnen at the Bellevue Medical Center in New York City, stated in an article entitled “Ozone in Medicine,” that ozone was commonly used worldwide in: herpes, AIDS, flu, wounds, burns, staph infections, fungal and radiation injuries, gangrene, colitis, fistula, hemorrhoids anal infections, virus infections, hepatitis, cancer, diabetes, arteriosclerosis, periodontal disease, intestinal and bladder inflammations. Ozone baths can be used to treat eczema and skin ulcers, ozone salve can treat skin ulcers and fungal growths.

- 1992: The Federal Technology Alert released a case study on the effects of ozone generation in cooling towers. In presenting the validity for such use by governmental agencies, they used a case study performed by NASA’s Kennedy Space Center in Florida. In this study, four 2,500 ton ceramic-filled concrete cooling towers were targeted as subjects for ozone generation. These cooling towers were used specifically to reject heat from air conditioning systems that provided humidity and temperature control for and during space shuttle processing. The ozone system was plugged in to operate at only 60% of capacity as a means of testing the system without using its full capability. The study lasted a year and was more than conclusive in its findings. During the study, ozone concentration rates were changed to between 30 and 40% and eventually decided upon as the optimal concentration rates for this particular operation. Not only was blowdown (the process of xxx) significantly reduced, but the annual projected water savings was staggering. The ozone generation system decreased water usage by 35.7 million gallons. In this case, and because of the large scope of the project, the unit cost $320,500, but the expected savings in water and chemical costs more than made up for it.

- The testers at NASA determined that since chemicals would no longer have to be used (as ozone provides all the benefits of chemical treatment and then some), the expected savings coupled with the decrease in the cost of water would provide a life cycle cost savings $800,000, a 3:1 savings ratio.
- The Executive Order 12856, required that federal agencies achieve a 50% reduction in the use of toxic chemicals and or toxic pollutants by December 31, 1999. In FTA, it reports and recognized ozone as having the potential for federal usage based on energy savings. Ozone greatly reduces or eliminates hazardous chemical storage and decreases safety concerns from operational and liability circumstances. In fact it greatly enhances compliance with most of it studies. It also outlines ozone’s reduction of a number of air and waterborne viruses and illnesses.
- 2000: A Food Additive Petition (FAP) requesting FDA approval of ozone as an antimicrobial agent for direct contact with foods was submitted in August and was approved by the FDA in 2001.
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